Plasmodium falciparumSpatial Analysis, Western Kenya Highlands
نویسندگان
چکیده
منابع مشابه
Plasmodium falciparum Spatial Analysis, Western Kenya Highlands
We carried out a population-based study to determine the unbiased, age-specific Plasmodium falciparum prevalence, asexual and sexual parasite density, and spatial distribution to establish rates of infection at a site in western Kenya. Three cross-sectional surveys were carried out in western Kenya highlands. Blood samples were taken from 1,388 persons from 6 months to 75 years of age. Parasite...
متن کاملPlasmodium falciparum genetic diversity in western Kenya highlands.
The present study examined the genetic diversity and population structure of Plasmodium falciparum in western Kenya by analyzing the polymorphism of 12 microsatellite loci and two antigen loci. Malaria in highland areas is unstable and epidemic whereas malaria in lowland areas is endemic. Transmission intensity and malaria prevalence are substantially lower in the highlands than in the lowlands...
متن کاملA cohort study of Plasmodium falciparum infection dynamics in Western Kenya Highlands
BACKGROUND The Kenyan highlands were malaria-free before the 1910s, but a series of malaria epidemics have occurred in the highlands of western Kenya since the 1980s. Longitudinal studies of the genetic structure, complexity, infection dynamics, and duration of naturally acquired Plasmodium falciparum infections are needed to facilitate a comprehensive understanding of malaria epidemiology in t...
متن کاملClinical Epidemiology of Malaria in the Highlands of Western Kenya
Malaria in the highlands of Kenya is traditionally regarded as unstable and limited by low temperature. Brief warm periods may facilitate malaria transmission and are therefore able to generate epidemic conditions in immunologically naive human populations living at high altitudes. The adult:child ratio (ACR) of malaria admissions is a simple tool we have used to assess the degree of functional...
متن کاملMolecular epidemiology of drug-resistant malaria in western Kenya highlands
BACKGROUND Since the late 1980s a series of malaria epidemics has occurred in western Kenya highlands. Among the possible factors that may contribute to the highland malaria epidemics, parasite resistance to antimalarials has not been well investigated. METHODS Using parasites from highland and lowland areas of western Kenya, we examined key mutations associated with Plasmodium falciparum res...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2005
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1110.050106